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Hunki Paek, PhD

  • Associate Research Scientist in the Department of Otolaryngology—Head & Neck Surgery
Hunki Paek, PhD

Hunki Paek, Ph.D., currently serves as Associate Research Scientist at Columbia University Medical Center, where he specializes in basic science research regarding the hearing loss and potential therapy. Dr. Hunki Paek graduated from Korea University and obtained his Ph.D. of Genetics and Neuroscience in Albert Einstein College of Medicine. After his Ph.D. he started to work at Columbia University Medical Center investigating cell surface markers of putative quiescent adult neural stem cells from their in vivo niche and characterizing a novel protein PDZD8 involved in ER-Mitochondrial tethering of neurons in the mouse brain. At Columbia University Medical Center the research of Dr. Hunki Paek is focused on understanding cellular and molecular changes in the peripheral/central auditory system in response to noise-induced hearing loss.

Languages Spoken

  • Korean

Lab Locations

  • College of Physicians and Surgeons (P&S)

    630 West 168th Street
    9th floor
    New York, NY 10032

Contact Info

NIH Grants

  • CONTRIBUTION OF GENETIC FACTORS TO SUDDEN NOISE-INDUCED HEARING LOSS (NY State Gov)

    Apr 1 2015 - Jun 30 2019

    PROSPECTIVE PURIFICATION OF ADULT STEM CELL ASTROCYTES (Federal Gov)

    Sep 1 2011 - May 31 2017

    CONTRIBUTION OF GENETIC FACTORS TO SUDDEN NOISE-INDUCED HEARING LOSS (NY State Gov)

    Apr 1 2015 - Mar 1 2017

    MICRORNA REGULATION OF ADULT NEURAL STEM CELLS (NY State Gov)

    Mar 1 2013 - Feb 29 2016

    MICRORNA REGULATION OF ADULT NEURAL STEM CELLS (NY State Gov)

    Mar 1 2013 - Feb 28 2016

    THREE DIMENSIONAL HIGH RESOLUTION RECONSTRUCTION OF THE INVIVO ADULT NEURAL STEM CELL NICHE (NY State Gov)

    Mar 1 2013 - Feb 28 2015

    THREE DIMENSIONAL HIGH RESOLUTION RECONSTRUCTION OF THE INVIVO ADULT NEURAL STEM CELL NICHE (NY State Gov)

    Mar 1 2013 - May 31 2013

Publications

1. Hirabayashi, Y.*, Kwon, S.*, Paek, H., Pernice, W., Paul, M., Lee, J., Erfani, P., Raczkowski, A., Petrey, D., Pon, L. and Polleux F. ER-mitochondria tethering by PDZD8 regulates

Ca2+ dynamics in mammalian neurons (2017). Science 358, 623-630. (*Co-first authors)

2. Paek, H., Antoine, M., Diaz, F. and Hébert, J. M. Increased ?-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics (2012). Developmental Dynamics 241, 242-246

3. Paek, H., Hwang,J., Zukin, S. and Hébert, J. M. (2011) ?-catenin-dependent FGF signaling sustains cell survival in the anterior embryonic head by countering Smad4. Developmental cell 20,689-699.

4. Maier, E., von Hofsten, J., Nord, H., Fernandes,M., Paek, H., Hébert, J. M. and Gunhaga, L. (2010). Opposing activities of FGF and BMP regulate the olfactory sensory versus respiratory epithelial cell fate decision. Development 137, 1601-1611.

5. Paek, H., Gutin, G. and Hébert, J. M. (2009). FGF signaling is strictly required to maintain early telencephalic precursor cell survival. Development 136, 2457-2465.

6. Gutin, G., Fernandes, M., Palazzolo, L., Paek, H., Yu, K., Ornitz, D. M., McConnell, S. K. and Hébert, J. M. (2006). FGF signaling generates ventral telencephalic cells independently of SHH. Development 133, 2937-2946.